Neuropathic pain in individuals with cancer remains a challenging clinical problem that requires advanced pharmacologic skills and a clear understanding of the molecular mechanisms that drive it. At ...

How can patients and clinicians effectively manage diabetic neuropathic pain in 2024? At the French Diabetes Society congress, three experts provided a comprehensive overview of the treatment for ...

In a recent study published in PNAS, researchers investigated the selective activity of sigmoid 2 receptor (σ2R) or transmembrane protein 97 (TMEM97) ligands on murine neuropathic pain models, their ...

In a paper published in the journal Neuron, researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic ...

Depending on the cause, nerve pain can become chronic, but there are many mediation options that can help. Nerve pain, also known as neuropathic pain, can come in various forms, from stabbing and ...

Nerve pain refers to painful sensations around the nerves. Various treatment options are available, including anticonvulsants, certain antidepressants, mild opioids, and some topical treatments.

Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer ...