Scientists at the Jackson Laboratory (JAX) have developed an antibody-based therapy against influenza A virus (IAV), which they suggest could change the way the world fights flu, one of the deadliest ...
A recent study published in the journal Nature Communications observed antibody breadth and effector functions as important immune correlates that can be used to develop universal influenza vaccines.
Humans mount convergent H1N1-H3N2 neutralizing antibody responses to influenza virus. Panels are derived from structures reported by Simmons et al., (PDB 7TRH, 7RRI and 3UBE by Xu et al., for the ...
(A) Cryo-EM structure overview of HSV-1 gB in complex with D48 Fab. The side view and top view were presented. The HSV-1 gB trimer and D48 Fab VH/VL were colored differently. (B) Neutralization assay ...
Antibodies, also known as immunoglobulins, are specialized proteins produced by the immune system to identify and neutralize foreign invaders, such as viruses, bacteria, and other pathogens. They are ...
A dual-action HIV antibody–drug conjugate forces Env to open, then blocks it, boosting virus neutralization up to tenfold in the lab.
Remember the 2016 Olympics in Brazil? It was the year Brazil defeated Germany in the final game of the men's football (aka soccer) tournament, but it was also the year when Zika virus made its entry ...
A Statistical Immune Correlates of Protection Model for Predicting Efficacy from Neutralizing Antibody Titers to Establish Immunobridging of Monoclonal Antibodies for Prevention of COVID-19” was ...