Although epistasis is an important phenomenon in the genetics and evolution of complex traits, epistatic effects are hard to estimate. The main problem is due to the overparameterized epistatic ...

A penalized maximum likelihood method has been proposed as an important approach to the detection of epistatic quantitative trait loci (QTL). However, this approach is not optimal in two special ...

The three-factor analysis displayed in Output 26.3.3 generates this message: WARNING: Too many factors for a unique solution. The number of parameters in the model exceeds the number of elements in ...

This paper compares the performance of four estimation methods, including the maximum likelihood estimation method, which can be used in fitting operational risk models to historically available loss ...