Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring ...

Clinical evidence has long suggested that the use of GLP-1 medications is linked to lower substance use. It’s also been ...

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Emma Fenske, DO, Oregon Health & Science University (THE CONVERSATION) Addiction is ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...

A decades-long study suggests that your daily caffeine fix might be doing more than jolting you through morning meetings – it ...

(THE CONVERSATION) Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse ...